Hello,
So we have a problem where we are trying to load DLLs from a virtual directory in the IIS. Our instance is setup so we have a clean release package as our webroot, no extra DLLs in the /bin folder, instead we have a directory outside our webroot (but on the same machine) containing those custom DLLs (custom checkout handlers and such) and a virtual directory named Customizations pointing to that outside directory in the IIS.
In our web.config in the webroot we have a simple assemblyBinding to the virtual directory: